Editorial: Early Life Stress and Depression
نویسندگان
چکیده
منابع مشابه
Early life stress affects limited regional brain activity in depression
Early life stress (ELS) can alter brain function and increases the risk of major depressive disorder (MDD) in later life. This study investigated whether ELS contributes to differences in regional brain activity between MDD patients and healthy controls (HC), as measured by amplitude of low-frequency fluctuation (ALFF)/fractional (f)ALFF. Eighteen first-episode, treatment-naïve MDD patients and...
متن کاملHealth Related Quality of Life, Depression, Anxiety and Stress in
Abstract Background Awareness of factors associated with quality of life (QOL) in patients with beta-Thalassemia major (&beta-TM) is necessary to develop clinical programs in order to improve social support and QOL in &beta-TM patients. This study aimed to examine QoL, depression, anxiety, and stress in &beta-TM patients in Ahvaz, Iran. Materials and Method A cross-sectional study w...
متن کاملIncreased stress-induced inflammatory responses in male patients with major depression and increased early life stress.
OBJECTIVE The authors sought to determine innate immune system activation following psychosocial stress in patients with major depression and increased early life stress. METHOD Plasma interleukin (IL)-6, lymphocyte subsets, and DNA binding of nuclear factor (NF)-kB in peripheral blood mononuclear cells were compared in medically healthy male subjects with current major depression and increas...
متن کاملEditorial: Molecular Mechanisms for Reprogramming Hippocampal Development and Function by Early-Life Stress
The hippocampal formation is both a key component of the medial temporal lobe crucial for declarative memory and a main target of stress mediators (e.g., glucocorticoids and neuropeptides) and stress-related molecules (e.g., nutritional factors and cytokines). During the first weeks of life, the hippocampus significantly increases in volume (Zhang et al., 2005) and several critical developmenta...
متن کاملReduced nucleus accumbens reactivity and adolescent depression following early-life stress.
Depression is a common outcome for those having experienced early-life stress (ELS). For those individuals, depression typically increases during adolescence and appears to endure into adulthood, suggesting alterations in the development of brain systems involved in depression. Developmentally, the nucleus accumbens (NAcc), a limbic structure associated with reward learning and motivation, typi...
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ژورنال
عنوان ژورنال: Frontiers in Psychiatry
سال: 2020
ISSN: 1664-0640
DOI: 10.3389/fpsyt.2019.00964